We should definitely aim to do more studies that account for different people's conditions. As long as limitations are called out then it's fine imo.
A core reason why we need to do as many trials as possible for different interventions is that there's no one-size-fit all approach. I believe that some things will work for some and not others.
The bottleneck is in having a standard framework to validate the impact of interventions and understanding "whether or not it works for you" with empirical evidence (not anecdotes)
Your points are valid. However, I think it's important that we have standard frameworks for evaluating the impact of new interventions that aim to improve wellbeing (lifestyle changes, pills, neuromodulation)
The number of years a person has lived is a good metric but that means if we're trying something new now, we need to wait for X years before saying this has an effect. X in your example being someone reaching 120years.
Some participants were doing cold plunges for the first time and others had done it before.
For participant 7 (who is an experienced cold plunger) we could see clear changes in their alpha power (dropping during the stroop task - attention & rising during resting state/cold plunge - being more relaxed)
yep, this trial was to see if there were any neural effects. We plan to do a follow up study with a much larger cohort of people and also over many days. This will provide extra context for solid conclusions
haha yep that's correct. Observing how a single individual responds over time along side other contextual metrics of behavior, productivity will help nail down "why a person responds well vs. doesn't"
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[1] https://chatgpt.com/share/682499c9-0578-800e-aa5f-664a9a6a74...