There are numerous third-party software applications for iptables that try to facilitate setting up rules. Front-ends in textual or graphical fashion allow users to click-generate simple rulesets; scripts usually refer to shell scripts (but other scripting languages are possible too) that call iptables or (the faster) iptables-restore with a set of predefined rules, or rules expanded from a template with the help of a simple configuration file. Linux distributions commonly employ the latter scheme of using templates. Such a template-based approach is practically a limited form of a rule generator, and such generators also exist in standalone fashion, for example, as PHP web pages.

The term iptables is also commonly used to inclusively refer to the kernel-level components. x_tables is the name of the kernel module carrying the shared code portion used by all four modules that also provides the API used for extensions; subsequently, Xtables is more or less used to refer to the entire firewall (v4, v6, arp, and eb) architecture.

iptables requires elevated privileges to operate and must be executed by user root, otherwise it fails to function. On most Linux systems, iptables is installed as /usr/sbin/iptables and documented in its man pages, which can be opened using man iptables when installed. It may also be found in /sbin/iptables, but since iptables is more like a service rather than an "essential binary", the preferred location remains /usr/sbin.

iptables is a user-space application program that allows a system administrator to configure the tables provided by the Linux kernel firewall (implemented as different Netfilter modules) and the chains and rules it stores. Different kernel modules and programs are currently used for different protocols; iptables applies to IPv4, ip6tables to IPv6, arptables to ARP, and ebtables to Ethernet frames.