Unreal is trash for 2D. However, if I was making a 2D game, I'd use Defold or Godot or GameMaker or raylib or libGDX, not Unity. Only reason to use Unity for gamedev these days is if you wanna get a job at a mobile game company

Also, both are FPS / TPAA engines. Unreal especially. Sure, you can make it do other things, but it's just not a natural fit for, say, an isometric 4X game....not that there's an openly available AAA quality engine for that at all