On a Latinamerican keyboard (yet, that's a thing), the brances are not as convenient. IIRC, the ~ symbol isn't even around. Semicolon is shift+right right finger -- super odd compared to just pinky. And ^ is behind right-alt (the one in the photos shows where, but many don't actually have it printed on the keycap).
Here's a photo of the layout: https://image.shutterstock.com/shutterstock/photos/279261125...
As an Argentinian, I've no fucking idea why we have our own layout instead of just using ISO Spanish.
It doesn't look terrible, but believe me, switching to US English International was a one-way trip.