Also a long history of spurious statistical correlations where you find "possible" links.
e.g. for a while there was a scare for RF from overhead powerlines causing brain cancer.
Turns out, the issue is the statistics used to try and isolate an effect from a general population sample have bias: plug in any effect, and any grouping factor, and you'll probably observe a doubling of the risk.
This effect was the cause of a whole spate of "X may cause cancer" reports in the 2000s.
Except that we can! The oral microbiome can be modulated to get exactly what you’re asking: remove pathogens that are good at creating acid and replacing them with ones that are good at remineralizing.
Shameless plug for my company (Bristle Health) that is trying to do exactly that via oral microbiome testing and personalized recommendations and products to improve.
Interesting, can you tell more? I’ve tried oral probiotics without much effect.
Did notice a difference for a couple of days after taking antibiotics for a week for something else, but it quickly subsided (my regular micro biome probably quickly recolonised the mouth).
All the species in the probiotic have been clinically studied with evidence that supports improvement in the oral microbiome and reduction of oral disease. Although, for transparency, the mechanism of action of some of the probiotics is still unclear, and we're working on figuring that out to improve oral probiotics and products in the future.
Dose makes the poison. Literally any chemical in sufficient dose is poisonous