You definitely should get fact-specific advice from an immigration attorney. Is she looking to live in the U.S. permanently or just work here when there's work?
It's going to be tough for her to get a work visa on her own doing what she does. A far-fetched option would be an O-1 through her own company or an E-2 through her own company; the former would require evidence of extraordinary ability in her field and the latter requires an investment by her of $75-100k USD.
