CAR-T is engineered to kill of CD19 expressing immune cells.
I’m sure you could take b-cell depleting antibodies as well and have it push your autoimmune disease into remission. And they are already used to treat autoimmune diseases like MS, Crohn’s, etc.
But depleting immune cells comes with a host of side effects. Risk of infection, even diseases that you’d otherwise easily fight off.
CAR-T is engineered to kill of CD19 expressing immune cells.
I’m sure you could take b-cell depleting antibodies as well and have it push your autoimmune disease into remission. And they are already used to treat autoimmune diseases like MS, Crohn’s, etc.
But depleting immune cells comes with a host of side effects. Risk of infection, even diseases that you’d otherwise easily fight off.