> Many of these genes are involved in immune system function—especially the innate immune system, the body's first line of defense against infections.
> The team also found that several of the genetic variants linked to unstable mRNA had already been associated with autoimmune diseases in large-scale genetic studies.
> [...]
> Using additional modeling, the researchers linked expression levels of these stability-regulated genes to diseases including allergic rhinitis, lupus, diabetes mellitus and multiple sclerosis.
Anyone here familiar with mRNA-targeted pharmacology? Even if "take this pill" only worked for 10% of those afflicted with such disorders, that'd still be a huge reduction in human suffering.
> The team also found that several of the genetic variants linked to unstable mRNA had already been associated with autoimmune diseases in large-scale genetic studies.
> [...]
> Using additional modeling, the researchers linked expression levels of these stability-regulated genes to diseases including allergic rhinitis, lupus, diabetes mellitus and multiple sclerosis.
Anyone here familiar with mRNA-targeted pharmacology? Even if "take this pill" only worked for 10% of those afflicted with such disorders, that'd still be a huge reduction in human suffering.