Absolutely. Six operands [1], each of which can be in a different memory page AND have an indirection via another memory page AND both the indirection and the final operand could if you're unlucky be misaligned and straddle two memory pages ... ow.

[1] MOVTC (Move Translated Character), MOVTUC (Move Translated Until Character), ADDP6 (Add Packed 6-operand)