I wonder whether the current huge funding in AI will ever lead to a revolution in computer architecture. Modern PCIe/CXL is already starting to blur the difference between memory and I/O. Maybe the future is going to be that CPUs, RAM, storage devices, GPUs and other devices are going to directly address one another like a mesh network. Maybe the entire virtual memory model will change to include everything to be addressed via a unified virtual memory space from a process/CPU perspective with simple read/write syscalls that translate into network packets flowing between the CPU and the destination (e.g. RAM/GPU/NVMe) and vice versa.
Don't we already almost (but not quite) have that? PCIe devices can talk directly to each other (still centralized AFAIK though) and from the programmers perspective everything you mentioned is mapped into a single unified address space prior to use (admittedly piecemeal via mmap for peripherals).
Technically there's nothing stopping me from mmaping an entire multi-terabyte nvme at the block level except for the part where I don't want to reimplement a filesystem from scratch in addition to needing to share it between lots of different programs.